Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

phenylalanine + H2O + O2 => phenylpyruvate + NH3 + H2O2

Definitions

Reviewed: Jassal, B, 2012-03-16 Edited: D'Eustachio, P, 2012-03-16 Authored: D'Eustachio, P, 2012-03-04 Extracellular IL4I1 catalyzes the reaction of phenylalanine, water, and molecular oxygen to form keto-phenylpyruvate, ammonia, and hydrogen peroxide. IL4I1, inferred to form a complex with FAD, has L-amino acid oxidase activity and with a strong preference for phenylalanine. The enzyme, found both in lysosomes and secreted into the extracellular space, is produced in the body by myeloid and dedritic cells (Boulland et al. 2007).

ID

http://purl.obolibrary.org/obo/HINO_0008200

comment

Reviewed: Jassal, B, 2012-03-16

Edited: D'Eustachio, P, 2012-03-16

Authored: D'Eustachio, P, 2012-03-04

Extracellular IL4I1 catalyzes the reaction of phenylalanine, water, and molecular oxygen to form keto-phenylpyruvate, ammonia, and hydrogen peroxide. IL4I1, inferred to form a complex with FAD, has L-amino acid oxidase activity and with a strong preference for phenylalanine. The enzyme, found both in lysosomes and secreted into the extracellular space, is produced in the body by myeloid and dedritic cells (Boulland et al. 2007).

definition source

Pubmed17356132

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/CHEBI_15377

http://purl.obolibrary.org/obo/CHEBI_15379

http://purl.obolibrary.org/obo/CHEBI_17295

has output

http://purl.obolibrary.org/obo/CHEBI_16134

http://purl.obolibrary.org/obo/CHEBI_16240

http://purl.obolibrary.org/obo/CHEBI_18005

label

phenylalanine + H2O + O2 => phenylpyruvate + NH3 + H2O2

prefixIRI

HINO:0008200

prefLabel

phenylalanine + H2O + O2 => phenylpyruvate + NH3 + H2O2

seeAlso

EC Number: 1.4.3.2

ReactomeREACT_120997

Reactome Database ID Release 432160492

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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