Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

PI3K/AKT Signaling in Cancer

Definitions

This pathway describes how normal signaling by PI3K/AKT, presented in the contained module 'PIP3 Activates AKT Signaling' and recently reviewed by Manning and Cantley in 2007, is perturbed in cancer, as described in the contained module 'Constitutive Signaling by PI3K/AKT'. Please refer to Liu et al. 2009 and Hollander et al. 2011 for recent reviews. Reviewed: Yuzugullu, Haluk, 2012-08-13 Reviewed: Zhao, Jean J, 2012-08-13 Edited: Matthews, L, 2012-08-03 Authored: Orlic-Milacic, M, 2012-07-18 Reviewed: Thorpe, Lauren, 2012-08-13

ID

http://purl.obolibrary.org/obo/HINO_0016282

comment

This pathway describes how normal signaling by PI3K/AKT, presented in the contained module 'PIP3 Activates AKT Signaling' and recently reviewed by Manning and Cantley in 2007, is perturbed in cancer, as described in the contained module 'Constitutive Signaling by PI3K/AKT'. Please refer to Liu et al. 2009 and Hollander et al. 2011 for recent reviews.

Reviewed: Yuzugullu, Haluk, 2012-08-13

Reviewed: Zhao, Jean J, 2012-08-13

Edited: Matthews, L, 2012-08-03

Authored: Orlic-Milacic, M, 2012-07-18

Reviewed: Thorpe, Lauren, 2012-08-13

definition source

Reactome, http://www.reactome.org

Pubmed21430697

Pubmed19644473

Pubmed17604717

label

PI3K/AKT Signaling in Cancer

located_in

http://purl.obolibrary.org/obo/NCBITaxon_9606

prefixIRI

HINO:0016282

prefLabel

PI3K/AKT Signaling in Cancer

seeAlso

Reactome Database ID Release 432219528

ReactomeREACT_147723

has_part

http://purl.obolibrary.org/obo/HINO_0016281

http://purl.obolibrary.org/obo/HINO_0016078

subClassOf

http://purl.obolibrary.org/obo/INO_0000021

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