National Cancer Institute Thesaurus

Last uploaded: October 28, 2019
Preferred Name

Pharmacologic Substance

Synonyms

Pharmacologic Substance

Agent

DRUG

Pharmacologic Agent

Pharmaceuticals

Pharmaceutical Agent

Drug Substance

Drug

drug

Pharmacological Substance

Product

Definitions

Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1909

ALT_DEFINITION

Article other than food intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease; or intended to affect the structure or any function of the body. not a device or a component, part, or accessory of a device. [from FDA Glossary of Terms, CDER] See also medicinal product, active substance.

An article other than food intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease; or intended to affect the structure or any function of the body. EXAMPLE(S): aspirin

An active natural, synthetic or semi-synthetic ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)).

Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also refers to a substance that alters mood or body function, or that can be habit-forming or addictive, especially a narcotic.

An article other than food intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease; or intended to affect the structure or any function of the body. EXAMPLE(S): aspirin OTHER NAME(S): NOTE(S):

CHEBI_ID

CHEBI:52217

code

C1909

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133805

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C96388

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C133855

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159503

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67497

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C90259

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C99078

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159501

Contributing_Source

BRIDG

NICHD

CDISC

FDA

CDISC-GLOSS

DEFINITION

Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances.

DesignNote

This category represents ingredients, not drug products.

FULL_SYN

Pharmacologic Substance

Agent

DRUG

Pharmacologic Agent

Pharmaceuticals

Pharmaceutical Agent

Drug Substance

Drug

drug

Pharmacological Substance

Product

Has_NICHD_Parent

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45306

label

Pharmacologic Substance

Legacy_Concept_Name

Pharmacologic_Substance

NICHD_Hierarchy_Term

Pharmacologic Substance

Preferred_Name

Pharmacologic Substance

prefixIRI

ncit:C1909

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C1254351

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1908

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